Inflammatory myofibroblastic tumor in colon
نویسندگان
چکیده
Inflammatory myofibroblastic tumor (IMT) is an uncommon mesenchymal solid tumor commonly documented in children and young adults. Here, we report a case of IMT in colon confirmed pathologically after laparoscopic anterior resection. A 35-year-old man presented with anal bleeding after defecation for 2 weeks. Colonoscopy demonstrated a mass with shallow ulceration in the central area and irregular margin accompanied by intact mucosa in the descending colon. Computer tomography showed a well-demarcated and homogenous solitary mass in the descending colon. We performed laparoscopic anterior resection. This case was diagnosed as IMT after microscopic examination. The tumor was composed of a proliferation of spindle-shaped cells arranged in the hyaline material with chronic inflammatory cells, composed mainly of plasma cells and lymphocytes. Immunohistochemically, tumor cells were positive for smooth muscle actin, and vimentin, and negative for desmin, CD117 (c-kit), anaplastic lymphoma kinase-1.
منابع مشابه
Infantile Inflammatory Myofibroblastic Tumor with Terminal Ileum Obstruction
Inflammatory myofibroblastic tumor is an uncommon benign neoplasm and its presentation in small bowel is rare. Due to clinical manifestation, laboratory data and radiologic results, there is an increased risk of over diagnosis as malignant tumors particularly malignant lymphoma in childhood therefore may be resulting in wrong therapeutic approach. However pathologic findings could be demonstrat...
متن کاملInflammatory Myofibroblastic Tumor of the Larynx: A Case Report
Introduction: Inflammatory myofibroblastic pseudotumors are initially described in the lung and various extrapulmonary sites such as the orbits, palatine tonsils, ears, gingiva, pterygomaxillary space, and periodontal tissues. These tumors rarely involve the larynx and predilection to the glottis occurs in an indolent manner. Case Report This case describes a laryngeal myofibroblastic tumor i...
متن کاملSuccessful treatment of inflammatory myofibroblastic tumor by surgical resection and radiotherapy: A case report
Background: Inflammatory myofibroblastic tumor (IMT) is a tumor composed of myofibroblasts and a mixed inflammatory infiltrate that rarely undergoes malignant transformation. The most common sites of involvement include the lung, liver and orbit, but it has been reported to occur in nearly every site of the body, including oral cavity and soft tissue. Although common in other sites, such a tumo...
متن کاملInflammatory Myofibroblastic Tumor of the Parotid Gland: A Rare Case Report
Inflammatory Myofibroblastic Tumor (IMT) is an uncommon benign neoplasm with unknown etiology that rarely affect parotid gland. Clinical and pathologic diagnosis of this neoplasm is difficult and is occasionally misdiagnosed as malignant. This reports presents the case of a 42 year old woman with IMT in the right parotid gland. Using fine needle aspiration cytology, pleomorphic adenoma and muco...
متن کاملInflammatory myofibroblastic tumor with extensive involvement of the bowel in a 7-year-Old child.
We present a case of unusual localization of inflammatory fibroblastic tumor in the terminal ileum, cecum, and ascending colon in a 7-year-old child. Segmental resection of the terminal ileum, cecum, and ascending colon with a tumor mass up to 6 cm in diameter was performed. Pathohistological examination of biopsy specimen was performed on routine hematoxylin-eosin sections, as well as immunohi...
متن کامل